Article
Five loci, SLT1 to SLT5, controlling the susceptibility to spontaneously occurring lung cancer in mice.
Cancer research - 15 Sept 2005
Wang Daolong, You Ming
Abstract excerpt
A series of linkage studies was previously conducted to identify quantitative trait loci associated with chemically induced lung tumors. However, little is known of genetic susceptibility to spontaneously occurring lung tumorigenesis (SLT) in mice. In this study, we did a whole-genome linkage disequilibrium analysis for susceptibility to SLT in mice using approximately 135,900 single-nucleotide polymorphisms...
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