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Article

Contrasting epistatic interactions between rat quantitative trait loci controlling mammary cancer development.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 2009

Piessevaux Géraldine, Lella Virginie, Rivière Michèle, Stieber Daniel, Drèze Pierre, Szpirer Josiane, Szpirer Claude

Abstract excerpt

We previously defined quantitative trait loci (QTLs) that control susceptibility to 7,12-dimethylbenz(alpha)anthracene-induced mammary carcinoma in SPRD-Cu3 (susceptible) and WKY (resistant) rats. Two of these QTLs, assigned to chromosomes (Chr) 10 and 18, control tumor growth rate and invasiveness. In this study we characterized a congenic strain in which a large segment of WKY Chr 10 was introduced in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins c-bcl-2

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Identifiers

PMID: 19052818
DOI: 10.1007/s00335-008-9155-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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