Article
Use of quantitative trait loci to map murine lung tumor susceptibility genes.
Experimental lung research - 1 Jan 2000
Devereux T R, Kaplan N L
Abstract excerpt
During the last decade new methods for mapping quantitative trait loci (QTLs) have helped geneticists uncover disease-associated genes. Genetic dissection of complex multigenic diseases such as cancer is being accomplished in part by mapping QTLs in experimental crosses of mice [1]. With the rece...
Topics
- Animals
- Chromosome Mapping
- DNA, Neoplasm
- Disease Models, Animal
- Gene Expression Regulation, Neoplastic
- Genetic Linkage
- Genetic Predisposition to Disease
- Inbreeding
- Lung Neoplasms
- Mice
- Mice, Inbred A
- Mice, Inbred C57BL
