Article
Use of quantitative trait loci to map murine lung tumor susceptibility genes.
Experimental lung research - 1 Jan 2000
Devereux T R, Kaplan N L
Abstract excerpt
During the last decade new methods for mapping quantitative trait loci (QTLs) have helped geneticists uncover disease-associated genes. Genetic dissection of complex multigenic diseases such as cancer is being accomplished in part by mapping QTLs in experimental crosses of mice [1]. With the recent construction of dense genetic linkage maps for the mouse, mapping of quantitative trait loci has become practical...
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