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Article

A locus on chromosome 8 controlling tumor regionality-a new type of tumor diversity in the mouse lung.

International journal of cancer - 1 Jun 2010

Quan Lei, Hutson Alan, Demant Peter

Abstract excerpt

Regional specificity of lung tumor formation has rarely been studied in mouse or human. By using crosses of strains semi-congenic for lung cancer susceptibility locus Sluc20, we have analyzed the genetic influences of Sluc20 and 5 other loci on tumor regionality in the mouse lung. We have mapped Sluc20 to a 27.92-MB proximal region of chromosome 8 and found that it controls the number and load of only those...

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Identifiers

PMID: 19847808
DOI: 10.1002/ijc.24983
PMCID: PMC2921316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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