Article
Genes responsible for quantitative regulation of antibody production.
Critical reviews in immunology - 1 Jan 1996
Puel A, Mouton D
Abstract excerpt
Evidence is first presented demonstrating that the individual capacity for antibody responsiveness has an inheritable component. The main evidence consists of spontaneous mutations causing either immunodeficiency or predisposition to autoimmunity in human and animals, and the involvement of some obvious candidate genes (in particular those belonging to the highly polymorphic histocompatibility and Igh loci),...
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