Article
Genetics of immunological tolerance: I. Bidirectional selective breeding of mice for oral tolerance.
Research in immunology - 1 Feb 1998
da Silva A C, de Souza K W, Machado R C, da Silva M F, Sant'Anna O A
Abstract excerpt
The polygenic nature of oral tolerance regulation was elucidated by the method of bidirectional selective breeding of mouse strains for tolerance susceptibility (TS) and resistance (TR) starting from a genetically heterogeneous population achieved by the equilibrated intercrossing of eight inbred mouse strains (A/J, DBA/2J, P/J, SWR/J, SJL/J, CBA/J, BALB/cJ and C57BL/6J). Seven days after intragastric...
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