Genetics of immunological tolerance: I. Bidirectional selective breeding of mice for oral tolerance.

doi:10.1016/s0923-2494(98)80298-8

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Article

Genetics of immunological tolerance: I. Bidirectional selective breeding of mice for oral tolerance.

Research in immunology - 1 Feb 1998

da Silva A C, de Souza K W, Machado R C, da Silva M F, Sant'Anna O A

Abstract excerpt

The polygenic nature of oral tolerance regulation was elucidated by the method of bidirectional selective breeding of mouse strains for tolerance susceptibility (TS) and resistance (TR) starting from a genetically heterogeneous population achieved by the equilibrated intercrossing of eight inbred...

Topics

Administration, Oral
Animals
Breeding
Cattle
Crosses, Genetic
Female
Immune Tolerance
Male
Mice
Mice, Inbred Strains
Models, Genetic
Ovalbumin
Phenotype
Selection, Genetic
Serum Albumin, Bovine

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