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Article

Identification of two quantitative trait loci involved in antibody production on mouse chromosome 8.

Immunogenetics - 1 Mar 1998

Puel A, Mevel J C, Bouthillier Y, Decreusefond C, Fridman W H, Feingold N, Mouton D

Abstract excerpt

Several quantitative trait loci (QTLs) contributing to the extreme phenotypes of the selected high (H) and low (L) antibody-responder lines of mice were mapped on distinct chromosomes. Successive backcrosses were bred to reduce the length of the QTL-bearing segment detected on chromosome 8 and to produce congenic lines to test gene effect independently of the other QTLs. An increase in antibody responses was...

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PMID: 9472069
DOI: 10.1007/s002510050365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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