Identification of two quantitative trait loci involved in antibody production on mouse chromosome 8.

doi:10.1007/s002510050365

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Article

Identification of two quantitative trait loci involved in antibody production on mouse chromosome 8.

Immunogenetics - 1 Mar 1998

Puel A, Mevel J C, Bouthillier Y, Decreusefond C, Fridman W H, Feingold N, Mouton D

Abstract excerpt

Several quantitative trait loci (QTLs) contributing to the extreme phenotypes of the selected high (H) and low (L) antibody-responder lines of mice were mapped on distinct chromosomes. Successive backcrosses were bred to reduce the length of the QTL-bearing segment detected on chromosome 8 and to...

Topics

Animals
Antibody Formation
Chromosomes
Crosses, Genetic
Female
Genetic Markers
Male
Mice
Mice, Inbred Strains
Microsatellite Repeats
Phenotype
Quantitative Trait, Heritable

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