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Article

The intraclonal diversity and control of antibody isotype switch recombination.

International immunology - 1 Jan 1990

Manser T

Abstract excerpt

The configuration of the expressed and unexpressed IgH alleles within two groups of hybridomas, both derived from single clones of B cells at an intermediate stage of the immune response of one mouse, were characterized. The data obtained confirm that individual 'naive' B cells are totipotent in their capacity to generate, via deletions in the IgH locus, offspring that express different IgG isotypes. Further, the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 2279002
DOI: 10.1093/intimm/2.9.893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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