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Article

Co-localization of quantitative trait loci regulating resistance to Salmonella typhimurium infection and specific antibody production phenotypes.

Microbes and infection - 1 Nov 2002

Trezena Aryene Goes, Souza Carla Martins, Borrego Andrea, Massa Solange, Siqueira Maria, De Franco Marcelo, Sant'Anna Osvaldo Augusto

Abstract excerpt

Salmonella enterica serotype typhimurium is a facultative intracellular bacteria that induces systemic infection in mice. Resistance to this pathogen is under polygenic control in which Nramp1 is the major gene involved. Lines of mice obtained by selective breeding for high (HIII) or low (LIII) antibody response to flagellar antigens of salmonellae showed significant susceptibility differences, although both the...

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PMID: 12475631
DOI: 10.1016/s1286-4579(02)00023-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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