Article
Differential effects of parathyroid hormone fragments on collagen gene expression in chondrocytes.
The Journal of cell biology - 1 Nov 1996
Erdmann S, Müller W, Bahrami S, Vornehm S I, Mayer H, Bruckner P, von der Mark K, Burkhardt H
Abstract excerpt
The effect of parathyroid hormone (PTH) in vivo after secretion by the parathyroid gland is mediated by bioactive fragments of the molecule. To elucidate their possible role in the regulation of cartilage matrix metabolism, the influence of the amino-terminal (NH2-terminal), the central, and the carboxyl-terminal (COOH-terminal) portion of the PTH on collagen gene expression was studied in a serum free cell...
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