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Article

Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways.

American journal of physiology. Endocrinology and metabolism - 1 Sept 2001

Carpio L, Gladu J, Goltzman D, Rabbani S A

Abstract excerpt

Parathyroid hormone (PTH)-related peptide (PTHrP) can modulate the proliferation and differentiation of a number of cell types including osteoblasts. PTHrP can activate a G protein-coupled PTH/PTHrP receptor, which can interface with several second-messenger systems. In the current study, we have examined the signaling pathways involved in stimulated type I collagen and alkaline phosphatase expression in the...

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Identifiers

PMID: 11500304
DOI: 10.1152/ajpendo.2001.281.3.E489

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PTH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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