Article

Parathyroid Hormone Related Protein (PTHrP)-Associated Molecular Signatures in Cell Signaling during Tissue Differentiation and in Non-tumoral Diseases

2023-05-17

Abstract excerpt

Parathyroid-hormone-related protein (PTHrP) is encoded by PTHLH gene which, by alternative promoter usage and splicing mechanisms, can give rise to at least three isoforms of 139, 141 and 173 amino acids with distinct C-terminals. PTHrP is subjected to different post-translational processing that generates smaller bioactive forms, comprising amino terminus, midregion (containing a nuclear/nucleolar targeting signa...

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Literature Corpus work: 20fb6df8-fdc9-5b5e-add2-7a0b5845e9e1
DOI: 10.20944/preprints202305.1184.v1

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