Article
Deciphering the genetic architecture of a multivariate phenotype.
Advances in genetics - 1 Jan 2001
Ghosh S, Majumder P P
Abstract excerpt
A heritable multivariate quantitative phenotype comprises several correlated component phenotypes that are usually pleiotropically controlled by a set of major loci and environmental factors. One approach to decipher the genetic architecture of a multivariate phenotype, in particular to map the underlying loci, is to reduce the dimensionality of the data by means of a data reduction technique, such as principal...
Topics
- Chromosome Mapping
- Computer Simulation
- Data Interpretation, Statistical
- Genetic Markers
- Humans
- Models, Statistical
- Multivariate Analysis
- Pedigree
- Phenotype
- Quantitative Trait, Heritable
- Recombination, Genetic
