Article
MCMC-based linkage analysis for complex traits on general pedigrees: multipoint analysis with a two-locus model and a polygenic component.
Genetic epidemiology - 1 Feb 2007
Sung Yun Ju, Thompson Elizabeth A, Wijsman Ellen M
Abstract excerpt
We describe a new program lm_twoqtl, part of the MORGAN package, for parametric linkage analysis with a quantitative trait locus (QTL) model having one or two QTLs and a polygenic component, which models additional familial correlation from other unlinked QTLs. The program has no restriction on number of markers or complexity of pedigrees, facilitating use of more complex models with general pedigrees. This is...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
