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Article

Two-locus approach of segregation and linkage analysis in the study of complex traits.

Genetic epidemiology - 1 Jan 1995

Xu J, Taylor E W, Panhuysen C I, Prenger V L, Koskela R, Kiemeney B, LaBuda M C, Maestri N E, Meyers D A

Abstract excerpt

A two-locus segregation and linkage-analysis approach was used to characterize the genetic control of a complex trait (Q1) and to localize the genes that have detectable effects. The results suggested that a two-locus Mendelian model fit the data significantly better than a one-locus model. The linkage results based on the most parsimonious two-locus model revealed linkage of Q1 to two areas (MG2 and MG3), while...

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PMID: 8788016
DOI: 10.1002/gepi.1370120649

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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