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Article

Two-locus approach of segregation and linkage analysis in the study of complex traits.

Genetic epidemiology - 1 Jan 1995

Xu J, Taylor E W, Panhuysen C I, Prenger V L, Koskela R, Kiemeney B, LaBuda M C, Maestri N E, Meyers D A

Abstract excerpt

A two-locus segregation and linkage-analysis approach was used to characterize the genetic control of a complex trait (Q1) and to localize the genes that have detectable effects. The results suggested that a two-locus Mendelian model fit the data significantly better than a one-locus model. The l...

Topics

Alleles
Chromosome Mapping
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 2
Evaluation Studies as Topic
Genetic Diseases, Inborn
Genetic Linkage
Genetic Markers
Humans
Models, Genetic
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Regression Analysis

Source

Identifiers

PMID: 8788016
DOI: 10.1002/gepi.1370120649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8788016-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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