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Article

Testing causal hypotheses in multivariate linkage analysis of quantitative traits: general formulation and application to sibpair data.

Genetic epidemiology - 1 Jan 1998

Todorov A A, Vogler G P, Gu C, Province M A, Li Z, Heath A C, Rao D C

Abstract excerpt

We provide a general framework for the development of model-free methods for the linkage analysis of multivariate phenotypic data. It is possible within this framework to test both for linkage of a set of phenotypes to one or more markers and for the presence of structural relations among the phenotypes themselves. This report presents the general model, paying special attention to the assumptions that enter its...

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Source

Identifiers

PMID: 9593113
DOI: 10.1002/(SICI)1098-2272(1998)15:3<263::AID-GEPI5>3.0.CO;2-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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