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Clinical, autoimmune, and genetic characteristics of very young children with type 1 diabetes. Childhood Diabetes in Finland (DiMe) Study Group.

Diabetes care - 1 Dec 1999

Komulainen J, Kulmala P, Savola K, Lounamaa R, Ilonen J, Reijonen H, Knip M, Akerblom H K

Abstract excerpt

OBJECTIVE: To study the characteristics of type 1 diabetes in very young children. RESEARCH DESIGN AND METHODS: Clinical outcome, islet cell antibodies (ICA), insulin autoantibodies (IAA), antibodies against GAD (GADA), IA-2 antibodies (IA-2A), and HLA-DQB1-defined genetic risk were analyzed in 35 children diagnosed with type 1 diabetes before 2 years of age and compared with those in 146 children who were...

Topics

Adolescent
Age Factors
Alleles
Autoantibodies
C-Peptide
Child
Child, Preschool
Diabetes Mellitus, Type 1
Genotype
Glutamate Decarboxylase
HLA-DQ Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

HLA-DQ beta-Chains

Humans

Insulin

Islets of Langerhans

Source

Identifiers

PMID: 10587824
DOI: 10.2337/diacare.22.12.1950

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