Article
IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus.
Journal of autoimmunity - 1 Jun 1996
Bennett S T, Wilson A J, Cucca F, Nerup J, Pociot F, McKinney P A, Barnett A H, Bain S C, Todd J A
Abstract excerpt
IDDM2-encoded predisposition to type 1 diabetes has recently been mapped to the minisatellite or variable number of tandem repeat (VNTR) locus upstream of the insulin and insulin-like growth factor II genes on human chromosome 11p15.5. In a UK case-control study (n = 228 sporadic diabetics; n = 4...
Topics
- Adolescent
- Adult
- Alleles
- Base Sequence
- Chronic Disease
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Gene Expression
- Genes
- Genotype
- HLA Antigens
- Humans
- Insulin
- Minisatellite Repeats
- Molecular Sequence Data