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Article

Insulin gene VNTR polymorphisms -2221MspI and -23HphI are associated with type 1 diabetes and latent autoimmune diabetes in adults: a meta-analysis.

Acta diabetologica - 1 Dec 2015

Zhang Na, Huang Weihuang, Dong Fang, Liu Yang, Zhang Baohuan, Jing Lipeng, Wang Man, Yang Guang, Jing Chunxia

Abstract excerpt

AIMS: A variable number of tandem repeat (VNTRs) region in the insulin gene (INS) possibly influences the progression of type 1 diabetes (T1D) and latent autoimmune diabetes in adults (LADA). However, effects of INS VNTR polymorphisms in these contexts remain inconclusive. METHODS: We performed a systematic review of work on the INS VNTR -2221MspI and -23HphI polymorphisms to estimate the overall effects thereof...

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Source

Identifiers

PMID: 26362169
DOI: 10.1007/s00592-015-0805-1

Genes

INS

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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