Article
Gtl2lacZ, an insertional mutation on mouse chromosome 12 with parental origin-dependent phenotype.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jan 1996
Schuster-Gossler K, Simon-Chazottes D, Guenet J L, Zachgo J, Gossler A
Abstract excerpt
We have produced a transgenic mouse line, Gtl2lacZ (Gene trap locus 2), that carries an insertional mutation with a dominant modified pattern of inheritance:heterozygous Gtl2lacZ mice that inherited the transgene from the father show a proportionate dwarfism phenotype, whereas the penetrance and expressivity of the phenotype is strongly reduced in Gtl2lacZ mice that inherited the transgene from the mother. On a...
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