Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of mice carrying a knockout-first and conditional-ready allele of transforming growth factor beta2 gene.

Genesis (New York, N.Y. : 2000) - 1 Sept 2014

Ishtiaq Ahmed A S, Bose Gracelyn C, Huang Li, Azhar Mohamad

Abstract excerpt

Transforming growth factor beta2 (TGFβ2) is a multifunctional protein which is expressed in several embryonic and adult organs. TGFB2 mutations can cause Loeys Dietz syndrome, and its dysregulation is involved in cardiovascular, skeletal, ocular, and neuromuscular diseases, osteoarthritis, tissue fibrosis, and various forms of cancer. TGFβ2 is involved in cell growth, apoptosis, cell migration, cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apoptosis
Share to beta-Galactosidase
Share to Cell Differentiation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Movement

Share to Cell Proliferation

Share to Epithelial-Mesenchymal Transition

Share to Transforming Growth Factor beta2

Source

Open in PubMed Open full text

Identifiers

PMID: 24895296
DOI: 10.1002/dvg.22795
PMCID: PMC4270118

Genes

TGFB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of mice carrying a knockout-first and conditional-ready allele of transforming growth factor beta2 gene.PMID 24895296Read ↗

Generation of mice with a conditional allele for transforming growth factor beta 1 gene.Semantic proximity Read ↗

TGFbeta2 knockout mice have multiple developmental defects that are non-overlapping with other TGFbeta knockout phenotypes.Semantic proximity Read ↗

Targeted mutations of transforming growth factor-beta genes reveal important roles in mouse development and adult homeostasis.Semantic proximity Read ↗

Generation of mice with a conditional allele for the transforming growth factor beta3 gene.Semantic proximity Read ↗

Newly developed TGF-β2 knock down transgenic mouse lines express TGF-β2 differently and its distribution in multiple tissues varies.Semantic proximity Read ↗

Biology of TGF-β in knockout and transgenic mouse modelsSemantic proximity Read ↗

Generation of mice with a conditional null allele for Tbx2.Semantic proximity Read ↗

Generating tamoxifen-inducible Cre alleles to investigate myogenesis in mice.Semantic proximity Read ↗

Generation of novel conditional and hypomorphic alleles of the Smad2 gene.Semantic proximity Read ↗

Generation of a mouse model for a conditional inactivation of Gtf2i allele.Semantic proximity Read ↗

Development of gene-switch transgenic mice that inducibly express transforming growth factor β1 in the epidermisSemantic proximity Read ↗

Multi-organ phenotypes in mice lacking latent TGFβ binding protein 2 (LTBP2).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.