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Article

DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state.

29 Oct 1996

Abstract excerpt

Transgenic mice expressing the sequences coding for the envelope proteins of the hepatitis B virus (HBV) in the liver have been used as a model of the HBV chronic carrier state. We evaluated the possibility of inducing a specific immune response to the viral envelope antigens and thus potentially controlling chronic HBV infection. Using HBV-specific DNA-mediated immunization in this transgenic model, we show that...

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Identifiers

PMID: 8901610
DOI: 10.1073/pnas.93.22.12496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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