Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immunobiology and Pathogenesis of Hepatocellular Injury in Hepatitis B Virus Transgenic Mice

20 Apr 1990

Abstract excerpt

The role of the immune response to hepatitis B virus (HBV)-encoded antigens in the pathogenesis of liver cell injury has not been defined because of the absence of appropriate experimental models. HBV envelope transgenic mice were used to show that HBV-encoded antigens are expressed at the hepatocyte surface in a form recognizable by major histocompatibility complex (MHC) class I-restricted, CD8+ cytotoxic T...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Immunotherapy and Immune Responses
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 1691527
DOI: 10.1126/science.1691527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immunobiology and Pathogenesis of Hepatocellular Injury in Hepatitis B Virus Transgenic MicePMID 1691527Read ↗

Pathogenetic effector function of CD4-positive T helper 1 cells in hepatitis B virus transgenic miceSemantic proximity Read ↗

A mechanism to explain the selection of the hepatitis e antigen-negative mutant during chronic hepatitis B virus infection.Semantic proximity Read ↗

Transgenic mouse models of hepatitis B virus‐associated hepatocellular carcinomaSemantic proximity Read ↗

Hepatitis B injury, male gender, aflatoxin, and p53 expression each contribute to hepatocarcinogenesis in transgenic mice.Semantic proximity Read ↗

DNA-mediated immunization in a transgenic mouse model of the hepatitis B surface antigen chronic carrier state.Semantic proximity Read ↗

Hepatitis B virus transgenic mice: Insights into the virus and the disease*1Semantic proximity Read ↗

Expression of hepatitis C virus envelope proteins in transgenic miceSemantic proximity Read ↗

Transgenic expression of entire hepatitis B virus in mice induces hepatocarcinogenesis independent of chronic liver injury.Semantic proximity Read ↗

Multiepitopic HLA-A*0201-restricted immune response against hepatitis B surface antigen after DNA-based immunization.Semantic proximity Read ↗

Exploring the biological basis of hepatitis B e antigen in hepatitis B virus infection.Semantic proximity Read ↗

Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice.Semantic proximity Read ↗

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.