Article
Multiepitopic HLA-A*0201-restricted immune response against hepatitis B surface antigen after DNA-based immunization.
Journal of immunology (Baltimore, Md. : 1950) - 15 Oct 2000
Loirat D, Lemonnier F A, Michel M L
Abstract excerpt
CTL together with anti-envelope Abs represent major effectors for viral clearance during hepatitis B virus (HBV) infection. The induction of strong cytotoxic and Ab responses against the envelope proteins after DNA-based immunization has been proposed as a promising therapeutic approach to mediat...
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