Article
Association of IA-2 autoantibodies with HLA DR4 phenotypes in IDDM.
Diabetologia - 1 Oct 1996
Genovese S, Bonfanti R, Bazzigaluppi E, Lampasona V, Benazzi E, Bosi E, Chiumello G, Bonifacio E
Abstract excerpt
Insulin, glutamate decarboxylase (GAD) and the protein tyrosine phosphatase-like molecule IA-2 are major targets of humoral autoimmunity in insulin-dependent diabetes mellitus (IDDM). These autoantibodies are heterogeneous with respect to age and patient human leukocyte antigen (HLA) phenotype. W...
Topics
- Alleles
- Autoantibodies
- Autoantigens
- Child
- Child, Preschool
- Diabetes Mellitus, Type 1
- Glutamate Decarboxylase
- HLA-DR3 Antigen
- HLA-DR4 Antigen
- Histocompatibility Testing
- Humans
- Immunophenotyping
- Infant
- Membrane Proteins
- Protein Tyrosine Phosphatase, Non-Receptor Type 1
- Protein Tyrosine Phosphatases
- Receptor-Like Protein Tyrosine Phosphatases, Class 8