Article
Associations of GAD65- and IA-2- autoantibodies with genetic risk markers in new-onset IDDM patients and their siblings. The Belgian Diabetes Registry.
Diabetes care - 1 Oct 1997
Vandewalle C L, Falorni A, Lernmark A, Goubert P, Dorchy H, Coucke W, Semakula C, Van der Auwera B, Kaufman L, Schuit F C, Pipeleers D G, Gorus F K
Abstract excerpt
OBJECTIVE: To investigate the association of GAD (65-kDa) autoantibodies (GAD65-Abs) and IA-2 autoantibodies (IA-2-Abs) with human leukocyte antigen (HLA)-DQ and insulin gene (INS) risk markers in patients with recent-onset IDDM and their siblings. RESEARCH DESIGN AND METHODS: Blood was sampled from 608 recent-onset IDDM patients and 480 siblings, aged 0-39 years and consecutively recruited by the Belgian...
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