Article
[Prevalence of immunologic markers (Anti-GAD and Anti-IA2) in first-degree relatives of patients with type I diabetes in the greater area of São Paulo].
Revista da Associacao Medica Brasileira (1992) - 1 Jan 2000
Cesarini Paulo Roberto, Mendonça Eurico, Fernandes Vânia, Silva Regina do Carmo, Morimitsu Lílian K, Garcia Fabíola E, Vechiatti Stella, Miranda Walkiria L, Dib Sergio Atala
Abstract excerpt
BACKGROUND: Increasingly accurate prediction of Type I Diabetes Mellitus (DMI), based on analysis of autoantibody markers, has become possible in first-degree relatives of patients with diabetes (PDMI). These markers indicate autoimmune process against pancreatic islet beta-cells. Anti-GAD and anti-IA2 are considered predictive of DMI, whose prevalences are considerably variable in different populations studied....
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