Article
Distinct genetic and immunological features in patients with onset of IDDM before and after age 40.
Diabetes care - 1 Apr 1997
Lohmann T, Sessler J, Verlohren H J, Schröder S, Rötger J, Dãhn K, Morgenthaler N, Scherbaum W A
Abstract excerpt
OBJECTIVE: Young age at onset is a relevant parameter associated with a rapid progression of IDDM. Our major aim was to define differences between IDDM patients with age at diagnosis > 40 years and adult IDDM with onset at a younger age. RESEARCH DESIGN AND METHODS: The correlation between islet-related antibodies (islet cell antibodies [ICAs] and antibodies [Abs] to GAD and the tyrosine phosphatase IA2), T-cell...
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