Article
Peculiar allelotype associated with susceptibility to neuroblastoma.
Genes, chromosomes & cancer - 1 Sept 1996
Perri P, Pession A, Mazzocco K, Strigini P, Iolascon A, Basso G, Tonini G P
Abstract excerpt
Human neuroblastoma (NB) is characterized genetically by deletions of the short arm of chromosome I and by MYCN amplification. Loss of heterozygosity (LOH) has been found frequently for region 1p36. We have studied restriction fragment length polymorphisms (RFLPs) by using anonymous and hypervari...
Topics
- Alleles
- Chromosome Deletion
- Chromosomes, Human, Pair 1
- Gene Amplification
- Gene Frequency
- Heterozygote
- Humans
- Neuroblastoma
