Article
Clinical categories of neuroblastoma are associated with different patterns of loss of heterozygosity on chromosome arm 1p.
The Journal of molecular diagnostics : JMD - 1 Feb 2000
Mora J, Cheung N K, Kushner B H, LaQuaglia M P, Kramer K, Fazzari M, Heller G, Chen L, Gerald W L
Abstract excerpt
Deletion of the short arm of chromosome 1 is frequently observed in neuroblastoma (NB). We performed loss of heterozygosity (LOH) analysis of 120 well characterized NB to better define specific regions of 1p loss and any association with clinical and biological prognostic features (DNA index, MYCN, age, and stage). All categories of disease were represented including 7 ganglioneuromas, 8 stage 4S, 33...
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