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Article

Allelic Loss of Chromosome 1p as a Predictor of Unfavorable Outcome in Patients with Neuroblastoma

25 Jan 1996

Abstract excerpt

BACKGROUND: Neuroblastoma is a childhood tumor derived from cells of the neural crest, with a widely variable outcome. Differences in the behavior and prognosis of the tumor suggest that neuroblastoma can be divided into several biologic subgroups. We evaluated the most frequent genetic abnormalities in neuroblastoma to determine their prognostic value. METHODS: We used Southern blot analysis to study the allelic...

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Identifiers

PMID: 8531999
DOI: 10.1056/nejm199601253340404

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Source receipt: pubmed, retrieved 7 Sept 2026.

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