Article
Prognostic relevance of genetic alterations in the p32 region of chromosome 1 in neuroblastoma.
European journal of cancer (Oxford, England : 1990) - 1 Oct 1997
Avigad S, Benyaminy H, Tamir Y, Luria D, Yaniv I, Stein J, Stark B, Zaizov R
Abstract excerpt
Thirty-six neuroblastomas were analysed for chromosome 1p alterations and their prognostic relevance. In 72% (26/36) of the patients, 1p alterations were identified in the tumours using 24 polymorphic loci ranging 1p22-1p36.3. LOH was identified in 25 children, and in 10 additional allelic imbala...
Topics
- Alleles
- Chromosomes, Human, Pair 1
- Humans
- Infant
- Loss of Heterozygosity
- Neuroblastoma
- Prognosis
- Survival Analysis
