Genetic alterations involving chromosome 1p in children with neuroblastoma.

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Article

Genetic alterations involving chromosome 1p in children with neuroblastoma.

Israel journal of medical sciences - 1 Aug 1994

Avigad S, Tamir Y, Yaniv I, Goshen J, Kaplinsky C, Cohen I J, Zaizov R

Abstract excerpt

Neuroblastoma is a common childhood tumor of the sympathetic nervous system, characterized by N-myc amplification and loss of heterozygosity (LOH) for sequences on chromosomes 1p, 11q and 14q. Using restriction fragment length polymorphism analysis, the constitutional and tumor genotypes were com...

Topics

Blotting, Southern
Child
Child, Preschool
Chromosome Deletion
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 11
Chromosomes, Human, Pair 14
Gene Amplification
Genotype
Heterozygote
Humans
Infant
Mutation
Neuroblastoma
Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 7913920

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7913920-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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