Article
Age-related 4,977 bp deletion in human lung mitochondrial DNA.
American journal of respiratory and critical care medicine - 1 Oct 1996
Fahn H J, Wang L S, Hsieh R H, Chang S C, Kao S H, Huang M H, Wei Y H
Abstract excerpt
The accumulation of mitochondrial DNA (mtDNA) mutations has been suggested to be an important contributor to human aging and degenerative diseases. The lung is exposed to ambient air and makes direct contact with the external environment. Numerous potentially noxious agents may damage lung tissue...
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