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Article

Respiratory function decline and DNA mutation in mitochondria, oxidative stress and altered gene expression during aging.

Chang Gung medical journal - 1 Jan 2000

Wei Yau-Huei, Wu Shi-Bei, Ma Yi-Shing, Lee Hsin-Chen

Abstract excerpt

Aging is a biological process that is characterized by the gradual loss of physiological function and increases in the susceptibility to disease of an individual. During the aging process, a wide spectrum of alterations in mitochondria and mitochondrial DNA (mtDNA) has been observed in somatic tissues of humans and animals. This is associated with the decline in mitochondrial respiratory function; excess...

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PMID: 19403001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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