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Article

Polycomb group protein Bmi1 promotes hematopoietic cell development from embryonic stem cells.

Stem cells and development - 1 Jan 2012

Ding Xiaolei, Lin Qiong, Ensenat-Waser Roberto, Rose-John Stefan, Zenke Martin

Abstract excerpt

Bmi1 is a component of the Polycomb repressive complexes and essential for maintaining the pool of adult stem cells. Polycomb repressive complexes are key regulators for embryonic development by modifying chromatin architecture and maintaining gene repression. To assess the role of Bmi1 in pluripotent stem cells and on exit from pluripotency during differentiation, we studied forced Bmi1 expression in mouse...

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Identifiers

PMID: 21545235
DOI: 10.1089/scd.2010.0539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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