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Article

MOZ and BMI1 act synergistically to maintain hematopoietic stem cells.

Experimental hematology - 1 Mar 2017

Sheikh Bilal N, Metcalf Donald, Voss Anne K, Thomas Tim

Abstract excerpt

Chromatin plays a central role in maintaining hematopoietic stem cells and during their stepwise differentiation. Although a large number of histone modifications and chromatin-modifying enzymes have been identified, how these act in concert to produce specific phenotypic outcomes remains to be established. MOZ (KAT6A) is a lysine acetyltransferase and enhances transcription at target gene loci. In contrast, the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27773671
DOI: 10.1016/j.exphem.2016.10.006

Genes

BMI1
PCGF2
PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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MOZ and BMI1 act synergistically to maintain hematopoietic stem cells.PMID 27773671Read ↗

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