Article
Discrimination of HLA-B27 alleles by group-specific amplification followed by solid-phase sequencing.
Human immunology - 1 Feb 1996
Blasczyk R, Weber M, van Lessen A, Schwella N, Huhn D, Salama A
Abstract excerpt
HLA-B27 is known to be highly associated with ankylosing spondylitis. Until now, nine B27 subtypes have been sequenced and may contribute in different fashions to ankylosing spondylitis. Additionally, the divergent subtypes may be of clinical importance in bone marrow transplantation with alternative donors. The purpose of this study was to determine the different subtypes of HLA-B27 by a direct sequencing...
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