Article
Remarkable polymorphism of HLA-B27: an ongoing saga.
Current rheumatology reports - 1 Oct 2010
Khan Muhammad Asim
Abstract excerpt
Histocompatibility antigen HLA-B27 is a normal gene that is distributed worldwide with variable prevalence and shows a remarkable association with ankylosing spondylitis and related spondyloarthropathies. The precise biological explanation for this remarkable association remains elusive. HLA-B27 represents a family of closely related proteins encoded by an ever-increasing number of alleles; there are 75 alleles...
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