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Article

Molecular typing of HLA-B27 alleles.

Immunogenetics - 1 Jan 1992

Dominguez O, Coto E, Martinez-Naves E, Choo S Y, López-Larrea C

Abstract excerpt

HLA-B27 represents a family of closely related antigens. Six alleles which differ in a limited number of nucleotide substitutions have been described (B*2701--B*2706). These changes are clustered in alpha 1 and alpha 2 domains. Polymerase chain reaction strategies were designed to amplify specific regions of class I exons 2 and 3. Amplified sequences were tested with eight sequence-specific oligonucleotides to...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Cell Line
Exons
Genotype
HLA-B27 Antigen
Humans
Molecular Sequence Data
Oligonucleotide Probes
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1644446
DOI: 10.1007/BF00215655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1644446-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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