Opposite orientations of an inverted duplication and allelic variation at the mouse agouti locus.

doi:10.1093/genetics/144.1.265

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Article

Opposite orientations of an inverted duplication and allelic variation at the mouse agouti locus.

Genetics - 1 Sept 1996

Chen Y, Duhl D M, Barsh G S

Abstract excerpt

The mouse agouti protein is a paracrine signaling molecule that causes yellow pigment synthesis. A pale ventral coloration distinguishes the light-bellied agouti (AW) from the agouti (A) allele, and is caused by expression of ventral-specific mRNA isoforms with a unique 5' untranslated exon. Mole...

Topics

Agouti Signaling Protein
Alleles
Animals
Base Sequence
DNA
Exons
Female
Genetic Variation
Genotype
Intercellular Signaling Peptides and Proteins
Male
Mice
Microsatellite Repeats
Molecular Sequence Data
Multigene Family
Proteins

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