Article
Human thymocyte responsiveness to stem cell factor: synergy with interleukin-2 for the generation of NK/LAK cytotoxicity.
Immunology letters - 1 Aug 1996
Uittenbogaart C H, Schmidc I, Kiertscher S, Shau H, Anisman D J, Zsebo K M, Clement L T
Abstract excerpt
Human recombinant stem cell factor (SCF) increases the viability and cell size of a subset of thymocytes in vitro, but does not independently induce phenotypic changes on thymocytes indicative of T cell differentiation. The SCF-responsive thymocytes have characteristics of large granular cells, that do not express T, B or NK cell-related antigens, and are primarily found in immature thymocyte subsets. These large...
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