Article
Characterization of two novel cell lines, DERL-2 (CD56+/CD3+/Tcry5+) and DERL-7 (CD56+/CD3-/TCRgammadelta-), derived from a single patient with CD56+ non-Hodgkin's lymphoma.
Leukemia - 1 Oct 2001
Di Noto R, Pane F, Camera A, Luciano L, Barone M, Lo Pardo C, Boccuni P, Intrieri M, Izzo B, Villa M R, Macrí M, Rotoli B, Sacchetti L, Salvatore F, Del Vecchio L
Abstract excerpt
Two novel IL2-dependent cell lines, DERL-2 and DERL-7, were established from a patient with hepatosplenic gammadelta T cell lymphoma. This patient presented, at diagnosis, two discrete populations of CD56+ cells, one TCRgammadelta+, the second lacking T cell-restricted antigens. The cell lines derived displayed features corresponding to the two cellular components of the disease: DERL-2 was...
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