Generation of natural killer-like cytotoxicity from human thymocytes with interleukin-2.

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Article

Generation of natural killer-like cytotoxicity from human thymocytes with interleukin-2.

Natural immunity and cell growth regulation - 1 Jan 2000

Gray J D, Torten M, Golub S H

Abstract excerpt

Human thymocytes cultured in the presence of an interleukin-2 (IL-2) source (the supernatant of the MLA 144 cell line) that contains no lectin or interferon (IFN) activity become cytotoxic to K562 target cells. Inclusion of allogeneic lymphoblastoid cells in these cultures results in the earlier...

Topics

Adjuvants, Immunologic
Animals
Antigens, Surface
Child
Cytotoxicity, Immunologic
Epitopes
Humans
Interferons
Interleukin-2
Killer Cells, Natural
Killer Factors, Yeast
Lymphocyte Activation
Mice
Phenotype
Protein Biosynthesis
Proteins
T-Lymphocytes, Cytotoxic
Thymus Gland

Source

Open in PubMed

Identifiers

PMID: 6209571

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-6209571-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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