Article
TNF-alpha potentiation of the lymphokine-activated killer response of murine thymus cells.
Lymphokine and cytokine research - 1 Apr 1994
Ujházy P, Maccubbin D, Eppolito C, Mihich E, Ehrke M J
Abstract excerpt
The role of tumor necrosis factor (TNF-alpha) on in vitro generation of lymphokine-activated killer (LAK) cells from murine thymocytes was investigated and compared to that on generation of LAK from splenocytes. TNF-alpha increased the potential of interleukin-2 (IL-2) at suboptimal concentrations to generate LAK activity in thymocytes even more than in splenocytes. In parallel, augmented [3H]thymidine uptake by...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
