Article
TNF-alpha potentiation of the lymphokine-activated killer response of murine thymus cells.
Lymphokine and cytokine research - 1 Apr 1994
Ujházy P, Maccubbin D, Eppolito C, Mihich E, Ehrke M J
Abstract excerpt
The role of tumor necrosis factor (TNF-alpha) on in vitro generation of lymphokine-activated killer (LAK) cells from murine thymocytes was investigated and compared to that on generation of LAK from splenocytes. TNF-alpha increased the potential of interleukin-2 (IL-2) at suboptimal concentration...
Topics
- Animals
- Antigens, Differentiation
- Cell Division
- Cytotoxicity, Immunologic
- Drug Synergism
- Female
- In Vitro Techniques
- Interleukin-2
- Killer Cells, Lymphokine-Activated
- Mice
- Mice, Inbred C57BL
- Phenotype
- Spleen
- T-Lymphocytes
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha
