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Article

Combined activation of murine lymphocytes with staphylococcal enterotoxin and interleukin-2 results in additive cytotoxic activity.

Cancer immunology, immunotherapy : CII - 1 Apr 1994

Belfrage H, Bhiladvala P, Hedlund G, Dohlsten M, Kalland T

Abstract excerpt

This report demonstrates that in vitro activation of murine spleen cells with interleukin-2 (IL-2) or the bacterial superantigen staphylococcal enterotoxin A (SEA) results in different patterns of activation and function of cytotoxic cells. Lymphokine-activated killer activity and antibody-dependent cellular cytotoxicity (ADCC) are mainly mediated by IL-2 activated natural killer (NK) cells. SEA is the most...

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Source

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Identifiers

PMID: 8168122
DOI: 10.1007/BF01533518
PMCID: PMC11038432

Genes

SEA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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