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Article

The role of SHIP in cytokine-induced signaling.

Reviews of physiology, biochemistry and pharmacology - 1 Jan 2003

Kalesnikoff J, Sly L M, Hughes M R, Büchse T, Rauh M J, Cao L-P, Lam V, Mui A, Huber M, Krystal G

Abstract excerpt

The phosphatidylinositol (PI)-3 kinase (PI3K) pathway plays a central role in regulating many biological processes via the generation of the key second messenger PI-3,4,5-trisphosphate (PI-3,4,5-P3). This membrane-associated phospholipid, which is rapidly, albeit transiently, synthesized from PI-4,5-P2 by PI3K in response to a diverse array of extracellular stimuli, attracts pleckstrin homology (PH)...

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Source

Identifiers

PMID: 12692707
DOI: 10.1007/s10254-003-0016-y

Genes

PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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