Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Is there a negative TRE in the luciferase reporter cDNA?

Thyroid : official journal of the American Thyroid Association - 1 Aug 1996

Maia A L, Harney J W, Larsen P R

Abstract excerpt

Transient expression assays using a luciferase (LUC) reporter gene are often used in studies of positive and negative thyroid hormone response elements (TREs) or of wild-type and mutated thyroid hormone receptors (TRs). However, unliganded TR (the beta isoform > than the alpha) increases LUC expression from 2 different TK-LUC vectors in several cell types, especially JEG-3 cells, and 3,5,3'-triiodothyronine (T3)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mutation
Share to Plasmids
Share to Rats

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Line

Share to Genes, Reporter

Share to Receptors, Thyroid Hormone

Share to Transfection

Source

Identifiers

PMID: 8875755
DOI: 10.1089/thy.1996.6.325

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is there a negative TRE in the luciferase reporter cDNA?PMID 8875755Read ↗

Negative and positive transcriptional regulation by thyroid hormone receptor isoforms.Semantic proximity Read ↗

Thyroid hormone receptors repress estrogen receptor activation of a TRE.Semantic proximity Read ↗

Enhancement of thyroid hormone receptor isoform specificity by insertion of a distant half-site into a thyroid hormone response element.Semantic proximity Read ↗

A Unique Role of the β-2 Thyroid Hormone Receptor Isoform in Negative Regulation by Thyroid HormoneSemantic proximity Read ↗

Ligand-independent and -dependent Functions of Thyroid Hormone Receptor Isoforms Depend upon Their Distinct Amino TerminiSemantic proximity Read ↗

Xenopus laevis alpha and beta thyroid hormone receptors.Semantic proximity Read ↗

Thyroid-hormone-dependent negative regulation of thyrotropin beta gene by thyroid hormone receptors: study with a new experimental system using CV1 cells.Semantic proximity Read ↗

Hormone-dependent and -independent transcriptional activation by thyroid hormone receptors are mediated by different mechanisms.Semantic proximity Read ↗

Rat Rev-erbA alpha, an orphan receptor related to thyroid hormone receptor, binds to specific thyroid hormone response elements.Semantic proximity Read ↗

Analysis of Thyroid Response Element Activity during Retinal DevelopmentSemantic proximity Read ↗

Pituitary NR4A1 is negatively regulated by thyroid hormone without direct binding of thyroid hormone receptors on the gene.Semantic proximity Read ↗

Thyroid Hormone Negatively Regulates the Transcriptional Activity of the β-Amyloid Precursor Protein GeneSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.