Article
Rat Rev-erbA alpha, an orphan receptor related to thyroid hormone receptor, binds to specific thyroid hormone response elements.
Molecular endocrinology (Baltimore, Md.) - 1 Mar 1994
Spanjaard R A, Nguyen V P, Chin W W
Abstract excerpt
Rat Rev-erbA alpha (rRev), which is related to thyroid hormone receptor (TR), is a conserved member of the nuclear hormone receptor superfamily whose physiological roles are unknown ("orphan" receptor). We studied DNA binding of rRev in vitro by electrophoretic mobility shift assay. A fusion prot...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Cloning, Molecular
- DNA
- DNA-Binding Proteins
- Dose-Response Relationship, Drug
- Genes, env
- Glutathione Transferase
- Ligands
- Molecular Sequence Data
- Mutation
- Nuclear Receptor Subfamily 1, Group D, Member 1
- Promoter Regions, Genetic
- Protein Binding
- Proteins
- Rats