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Article

Analysis of Thyroid Response Element Activity during Retinal Development

29 Oct 2010

Abstract excerpt

Thyroid hormone (TH) signaling components are expressed during retinal development in dynamic spatial and temporal patterns. To probe the competence of retinal cells to mount a transcriptional response to TH, reporters that included thyroid response elements (TREs) were introduced into developing retinal tissue. The TREs were placed upstream of a minimal TATA-box and two reporter genes, green fluorescent protein...

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PMID: 21060789
DOI: 10.1371/journal.pone.0013739

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